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Dear all, Anybody could explain to me what is the difference between crude type and purified enzyme? Why the IC50 value for both enzyme would be different when tested on particular inhibitor? Your...
10 April 2018 3,487 8 View
Anybody could suggest me any journal website that possibly accept negative bio-assay result in the research study has done? The project included computer modelling (docking study), chemical...
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Dear all, As far as i know, EC50 is the concentration of a drug that gives half-maximal response. The IC50 is the concentration of an inhibitor where the response (or binding) is reduced by half...
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Dear all, I have a compound with molecular formula C11H9BrN2O3S2, the molecular weight is about 361.23 Da, the predicted m/z value from chemdraw is 361.92 (100%), 359.92 (94.0%), however my real...
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Dear all, Currently i am running docking studies using AutodockTools 4.2. For the protein optimization stage, why do we need to add hydrogen atoms as well as charges into the protein? What is the...
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i have the full set nmr result for my compound included 1H, 13C, dept, cosy, hsqc & hmbc. However, some of my carbon peak (all quaternary C) didnt appeared. One of the proton showed...
20 February 2017 6,976 10 View
I have synthesized two different compounds. However, what a coincident both nmr spectrum showed an unknown peak (singlet, very intense) at the region of 2.4 - 2.6 ppm in proton nmr, 28 - 30 ppm in...
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