How do you calculate the fractional inhibitory concentration index (FICi) of two combinations of drugs, if their MICs are unknown?

For example, drug A's MIC is reported as >16microg/ml and that of B as >12.5microg/ml. The combined MIC that brings about synergy is 0.5microg/ml for drug A and 0.78microg/ml for drug B. How...

09 September 2016 4,036 4 View