Prem Sharma

4 Questions 2 Answers 0 Followers

Questions related from Prem Sharma

How to use two different GEO datasets in one transcriptomics analysis ?

I want to use two different datasets where one data will be for control while another data will for test samples. How can I use it. What will be the protocol including normalisation. Kindly help...

12 November 2023 4,372 1 View

How to identify bottleneck hub gene as potential drug target in cytoscape?

I have developed protein-protein network and define edge thickness based on combined-score in cytoscape. I am unable to identify bottleneck hub gene as drug target. I dont know how to use...

25 April 2022 4,306 0 View

How to read .cel file in r language for protein interaction network analysis?

I need to do protein-protein interaction network analysis for which dataset was downloaded from GEO datasets. Data is in the .cel format. I am unable to read these files. Please also suggest "How...

15 November 2019 3,059 2 View

I am confused with terms like docking score, glide score, XP gscore and binding energy?

I am doing docking where I do ligand preparation in which I develop multiple conformers for several molecules. I am not getting synchronized results. For one conformer binding energy is maximum...

25 October 2019 7,347 1 View