Pratap Subhashrao Patil

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Questions related from Pratap Subhashrao Patil

What are appropriate scavengers in the t-butyl group deprotection in peptide synthesis?

I have a peptide of 31 amino acid chain length, consisting of amino acids like histidine, arginine, tryptophan. I have to remove the t-butyl group from the alpha carboxyl of glutamic acid. I am...

17 October 2014 7,151 12 View

Can you suggest the coupling reagents for Fmoc-Ser(Ac)-OH in solid phase peptide synthesis?

We have to use Fmoc-Ser(Ac)-OH for the peptide synthesis (solid phase). We tried HOBt/HBTU/DIPEA combination. However, we didn't get any product. Tried to check the literature but it seems...

19 March 2014 9,014 8 View