Ping Liang

2 Questions 13 Answers 0 Followers

Questions related from Ping Liang

Does a fixed or high frequency variant always indicate a positive selection?

Many variants, such as the millions of mobile element insertions (MEIs), exist at a very high frequency with the majority become fixed in the human populations. Since the presence of MEIs happens...

25 March 2017 3,602 3 View

Genomic variants shown as deletions of entire introns: RNA contamination vs. possible processed pseudogenes?

In analysis of human genomic variants based on either WGS or WES, I often came across high impact variants shown as deletion of introns at their entirety. Since there is no known molecular...

02 August 2016 867 7 View