Patrick Aouad

5 Questions 26 Answers 0 Followers

Questions related from Patrick Aouad

How can we prove cancer-associated macropinocytosis clinically?

Insights about macropinocytosis have been gathered from in vitro and in vivo data, but the question remains; is this phenomenon seen clinically? or do we have the tools to prove it at least?

11 January 2018 4,770 2 View

Is there a fluorescent label that could be added to the medium prior to live-imaging that would enrich basement membrane components?

We are interested in imaging the basement membrane (BM) dynamics; I am kindly asking if there are any fluorescent labels with high affinity to BM components namely, collagen or laminin that would...

01 October 2017 7,289 2 View

Alginate Embedding in Paraffin

I am having troubles with the paraffin embedding. First, I am incubating my alginate in 4% PFA overnight, the next day I wash them in PBS then put them in 70% Ethanol. We have an automated...

03 August 2017 210 3 View

How do we calculate Drug Resistance Index (DRI)?

We have generated a cell line that is resistant to drug A. We now want to check for the DRI to compare the parental cell line (sensitive to drug A) to the resistant cell line. I have come across...

22 August 2016 2,660 4 View

Does exercise reverse cachexia in cancer patients?

Food for thought.

04 August 2016 671 3 View