Olivier Loget

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Questions related from Olivier Loget

How to calculate a PDE (Permitted Daily Exposure) for eye drops (dose-levels in µL per eye, not in mg/kg)?

I need to calculate a PDE (Permitted Daily Exposure) according to EMA guideline but usually we use dose-levels in mg/kg/day. How to manage eye drops (µL/eye). I assume the eye drop concentration...

15 May 2025 7,541 1 View

How to calculate a PDE for eye drops (dose-levels in µL per eye, not in mg/kg)?

I need to calculate a PDE but ususally we use dose-levels in mg/kg/day. How to manage eye drops (µL/eye). I assume the eye drop concentration has to be takene into consideration. Does it differ if...

15 May 2025 4,465 1 View