Oliver Karam

4 Questions 27 Answers 0 Followers

Questions related from Oliver Karam

If you had to participate in a RCT on plasma transfusion in critically ill patients, what trigger would you want to use?

When randomizing patients to two different plasma transfusion strategies, it is important to make sure the coagulation test used to differenciate both groups makes clinical sense. Would you use...

28 April 2015 1,300 10 View

Would you use ROTEM to target anti-coagulation in specific pathologies at high risk of thrombosis, such as post liver transplant?

ROTEM has been developed to guide physicians dealing with massively bleeding patients. However, it might be useful in other situations, such as hypercoagulable states. Would you consider using...

15 August 2014 7,290 12 View

Are plasma transfusions only given to patients who will benefit from them?

Epidemiological data suggest that plasma transfusions are associated with worse clinical outcomes (adult and pediatric data), and fail to correct mildly abnormal coagulation tests (adult data)....

25 November 2013 2,919 22 View

What would be the appropriate trigger for plasma transfusion?

Usually, physicians prescribe plasma transfusion to stop bleeding or to prevent a potential bleeding. However, studies have shown that common coagulation tests fail (aPTT, INR) to predict the risk...

14 November 2012 6,109 16 View