Nisha Rizvi

3 Questions 15 Answers 0 Followers

Questions related from Nisha Rizvi

What can you say about the pharmacology of the agonist/antagonist?

I am looking at the mechanism of action of a GPCR agonist on hippocampal physiology. An antagonist for the receptor does not block the peak agonist-effect, but changes irreversible effect to...

09 September 2014 4,241 9 View

Has anyone working with dopamine physiology/biochemistry in rats noticed unexplained variability/non-reproducibility in results?

Do you think the animals emotional state might be responsible? Ever tried publishing, what do reviewers say? Thanks

07 July 2014 6,101 11 View

How to run Co-IP in native tissue for membrane GPCRs?

I am running coimmunoprecipitation assay for GPCRs in native tissue. We are having problems with efficient elution (multiple elutions show bands with variable intensities). We have increased...

02 February 2014 3,108 5 View