Mohammed Khalid Pasha

4 Questions 9 Answers 0 Followers

Questions related from Mohammed Khalid Pasha

Can anyone share wth me reference articles for drug discovery, lead identification and optimization?

I am looking for articles with information pertaining to selection of NCEs with good PK properties . How to decide whether a PK profile is good or bad in terms of pharmacokinetics parameters.

08 August 2016 2,495 0 View

How do you analyze the metabolomics data when you are picking some ions (m/z) matching with the drugs?

Dear All I am doing the metabolomics data analysis. My PCA plot showed tight clustering of the QCs, so i went ahead for picking up the markers. To my surprise some of the ions were matching with...

06 June 2015 7,019 3 View

Can we expect well resolved peaks in a blank injection (methano: water) in a gradient program?

Dear All I am trying to develop a gradient method for metabolomics study. I programmed a gradient and tries to run blank injections containing methanol : water in the ratio of 1:1 using the...

04 April 2015 9,848 12 View

Can we use Concanavalin A in place of Phytohemagglutinin M to stimulate the lymphocytes?

I am working with lymphocyte cultures for micronucleus test. I am using PHA-M in my assays. I have a curiosity to use Concanavalin A in place of PHA-M to stimulate the lymphocytes. Can anyone...

01 January 2014 945 4 View