Moataz Ahmed Shaldam

3 Questions 6 Answers 0 Followers

Questions related from Moataz Ahmed Shaldam

What is the best scoring function for docking?

In the fields of computational chemistry and molecular modelling, scoring functions are fast approximate mathematical methods used to predict the strength of the non-covalent interaction (also...

18 April 2014 10,053 6 View

What are the processes for pharmacophore model development?

A pharmacophore is an abstract description of molecular features which are necessary for molecular recognition of a ligand by a biological macromolecule. The IUPAC defines a pharmacophore to be...

18 April 2014 7,942 4 View

Does the stereoselective form of the chiral 1,4-DHP calcium channel modulators show different activity on the receptor (agonist/antagonist)?

1,4-DHP can modulate the L-type calcium channels, the DHP ring has 3,5 ester substituents and 2,6 methyl group(most common). If these positions (3 and 5) or (2 and 6) have different substituents...

01 April 2014 2,484 3 View