Michael Cunningham

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Questions related from Michael Cunningham

How do I construct a violin plot from CLC Genomics Workbench mapping to reference of NextGen data?

We have mapped short-read data to a reference genome using CLC Genomics Workbench. The mapping looks good but we are unsure how to extract coverage per sites or coordinates for individual mapped...

30 August 2016 7,975 3 View

Can DNA be extracted from formalin fixed animal specimens?

DNA extraction from museum specimens offers a potential treasure chest of important questions relating to extinction, mutation and human impacts on genetic diversity through time. Most literature...

04 June 2014 3,467 9 View

Is the RelTime method implemented in MEGA6 a viable alternative to bayesian methods for estimating divergence times?

The RelTime algorithm of Tamura et al. (2012 PNAS 109:19333-8), has been available for some time in MEGA6 but I see few people using it. Why is that? What concerns do people have with this method...

10 April 2014 6,474 1 View

How do likelihood searches and evolutionary model tests in MEGA5 compare with those in other software?

MEGA is a really convenient program for editing and getting a feel for sequence data. The latest version has incorporated tests among models of sequence evolution and also phylogenetic likelihood...

19 February 2013 1,511 2 View