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Questions related from Michael Cukan
I am interested in the MTIOpenScreen compound libraries, NP-lib, FOOD-lib, and diverse-lib. Their paper describes how they created the sdf files, of course, but I was hoping these were available...
14 September 2023 3,900 0 View
The Wikipedia page on zinc fingers states that such domains exist; salt bridges reportedly take the place of zinc. However, there is no citation! The only example of a natural zinc-stabilized DNA...
08 July 2016 9,773 1 View
I require large amounts of small (16bp) dsDNA molecules for zinc finger binding studies. This is the major bottleneck in my research since the large amounts are expensive to purchase synthesized...
29 July 2015 4,875 3 View
I will be performing binding studies of various zinc fingers to DNA using ITC, which unfortunately requires a large amount of material. Commercially synthesized DNA would cost roughly US$10-$20...
07 November 2014 6,555 0 View
I want to further my career in biotechnology with a PhD. I've applied to a number of programs including a standard Molecular Cell Biology program as well as an Engineering program in the same...
24 January 2013 1,959 3 View
I am trying to develop a heparin affinity column method using a 100mM to 1M NaCl step elution. My protein of interest actually elutes at a 0.5M NaCl step, but though it elutes in a nice, sharp...
06 September 2012 2,928 3 View
