Md Adnan Karim

3 Questions 9 Answers 0 Followers

Questions related from Md Adnan Karim

How can I identify the positions and number of SNPs in a set of genomes?

I have 56 genome sequences aligned to one reference genome sequence. Now i want to identify the number of SNPs throughout the genomes, their positions to compare between the 56 query genomes. Is...

20 April 2020 7,255 1 View

How to run Multiple Sequence Alignment on large sequences using MUSCLE?

I have a FASTA file of 32 whole genome sequence, each ~30kbp long. I tried using MUSCLE for MSA as well as MEGA 5.1. But it shows error due to insufficient memory (RAM). My system has 8 gigs of...

19 April 2020 7,148 19 View

What could be a potential approach to correlate assay specific EC50 values to in silico data?

I have been trying to identify correlations between assay specific EC50 values to in silico data (binding free energy, residue specific hydrogen bond occupancy, MM/PBSA energy values) for a range...

01 January 1970 9,536 3 View