How do I interpret this Isothermal Titration Calorimetry (ITC) graph? Why are my heats of dilution so large?

I am trying to measure the binding between an aptamer (ssDNA) that 'supposedly' binds specifically to (+)-methamphetamine. The aptamer comes as a solid form, which I initially dilute in H20, and...

15 April 2025 5,559 1 View