Manuel Kaulich

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Questions related from Manuel Kaulich

Can We Address Cancer Plasticity/Heterogeneity with CRISPR/Cas?

Tumor cell plasticity is as a major cause of therapeutic failure and malignant relapse. Plasticity is caused by the presence of cellular sub-populations that react differently to intrinsic and...

04 April 2016 3,170 1 View

To assess or not to assess All potential off-targets? Can we find another way of assessing all potential off-targets other than deep-sequencing?

Turning a 'bacterial immune system' into a versatile tool to edit the genome, by now of multiple diverse organisms, has changed the field of biology. The impressive speed, with which genetically...

11 November 2014 8,079 15 View