Maarten van Beek

5 Questions 7 Answers 0 Followers

Questions related from Maarten van Beek

What are usual responses to von frey filaments in control sprague dawley rats?

I have control rats that developed mechanical hypersensitivity over time that is comparable to my experimental rats (streptozotocin induced DM). What filaments do female/male control/naive sprague...

10 October 2016 7,197 4 View

Should you give rats injected with streptozocin alternative food, perhaps with lower sugar content?

I've started my pilot and got 13 out of 15 SD rats diabetic with a i.p. strep injection of 65 mg/kg. At first everything looked fine and only 3 animals had values over 33.3 mmol/L glucose/ one...

01 January 2014 2,156 12 View

How to best counteract Hypoglycemia after STZ injection?

In the first days after STZ injection, my SD rats will develop a Hypoglycemia due to the insulin release from destroyed beta cells. I've seen some different protocols to counteract this...

12 December 2013 5,642 17 View

Is it possible to induce DM in rats 30 min after dissolving STZ?

I started my PhD project 3 months ago and I am running into some practical difficulties. Everybody seems to agree that STZ should be administered as quickly as possible after dissolving the agent,...

12 December 2013 5,494 27 View

What is the location of P-p38 MAPK?

In some articles a colocalization is found between microglial marker OX-42 and phosphorylated p38 MAPK. However the antibody I used (cell-signalling) only labels nuclear P-p38 and therefore I see...

12 December 2013 1,132 9 View