Lokesh Pathak

3 Questions 5 Answers 0 Followers

Questions related from Lokesh Pathak

If active loaded nanoparticles give lower value of IC50 than unloaded on HEK normal cells does that mean the formulation is toxic for normal cell?

In one of the assay it was found that nanoformulations were giving lower value means potent cytoxicity on HEK normal cells as compared to powdered form. Does that mean that nanoformulation is not...

03 March 2015 2,396 2 View

What time scale will be sufficient to model protein ligand interaction in MD simulation?

What time scale would be sufficient to show protein ligand interaction that we normally depict using molecular docking simulations. In addition what ensembles to use NVE or NPT while performing...

09 September 2014 8,481 7 View

Why after diluting the chitosan coated organic lipid nanoparticle had the suspension zeta potential of the particles incresed for my nanosuspension?

I have serially diluted the cationic chitosan nanoparticle solution and i found that the zeta potential in millivolts is increasing ? I could not understand this phenomenon on the basis of...

10 October 2013 1,739 7 View