Linda Koshy

4 Questions 12 Answers 0 Followers

Questions related from Linda Koshy

What is a scoping review?

In what context should we choose to do a scoping review? How is it different from systematic review, literature review, mapping review and Cochrane review? What are its mandatory or optional...

06 July 2020 8,375 3 View

If I use REVEL score as a meta-predictor for clinical variant classification, what would be a reasonable cut-off to filter disease variants?

Ioannidis et al., 2019, reported the development of the REVEL score (rare exome variant ensemble learner) for redefining pathogenic variant classification, and Tian et al., 2019, reported that...

30 March 2020 2,592 2 View

Identity score or e-value - what's the better measure for species identification in BLAST?

And what is a reliable threshold for these measures?

06 January 2015 6,328 4 View

What are the Mechanisms and pathways involved in hypertrophic cardiomyopathy?

Although hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by mutations predominantly in sarcomere genes, there are many mechanisms and pathways involved in HCM that leads...

01 January 1970 8,108 3 View