Laxit K Bhatt

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Questions related from Laxit K Bhatt

Is it possible for clinical studies to report higher exposure than achieved in the highest dose of the most relevant nonclinical toxicity study?

Is a scenario possible wherein the drug exposure achieved in clinical studies surpass or exceed than the exposure achieved in nonclinical toxicity studies conducted of appropriate duration? And if...

05 May 2019 598 4 View

How to perform administration of 1.0ml of injectable formulation by intramuscular route in rats?

Ethics prevent injecting more than 0.2ml of formulation per site per day in rodents. Then, how do we administer 1.0ml in one animal. The maximum possible is 0.8ml in four site. Body weight and...

02 February 2018 5,738 2 View