Laxit K Bhatt

3 Questions 6 Answers 0 Followers

Questions related from Laxit K Bhatt

Is inclusion of toxicokinetics in a repeat dose dermal toxicity study justifiable?

Most guidelines do not clearly instruct on designing toxickinetics study or inclusion of TK in a repeat dose dermal toxicity study. If TK is inlcuded, can it be justified?

22 January 2018 1,659 4 View

I am planning to perform an exploratory toxicity study. I have an option of using Wistar or SD Rats? Which should I prefer and why?

I am planning to initiate a single dose toxicity study in rats. And I have an option of using either the SD rats or Wistar Rats. Which strain should I choose? Do Wistar Rats have a preference over...

01 July 2016 340 1 View

Can an oral dose of 20 ml/kg be divided into 2 or 3 doses in rats? If yes, what time difference should be kept between each of them?

Along with the main question, is it required to keep he animals on fasting for the complete duration of dosing?

16 May 2016 7,208 7 View