Lavanya Ravichandran

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Questions related from Lavanya Ravichandran

Why do I see a heterozygous peak in Sanger sequencing of x linked gene in an adult male?

I have been working with the ABCD1 gene on the X chromosome. When males are hemizygous for genes in the X chromosome why do I get a heterozygous peak in Sanger sequencing of this gene even with...

16 April 2020 7,467 0 View

Why is phenotype correlated with the mildest mutation in autosomal recessive disorers?

in case of CAH, where patients harbor more than 1 mutation the phenotype is correlated with the mildest mutation instead of the one that severely affects enzyme function. Why is it so?

26 May 2019 2,633 6 View