Laura M. McLane

2 Questions 1 Answers 0 Followers

Questions related from Laura M. McLane

Can anyone recommend a good system to look at protein-DNA interactions that does not involve doing an EMSA?

I want to look at putative DNA binding mutants in my favorite protein but am trying to avoid doing EMSAs. Does anyone have a solid assay that they have used to look and protein-DNA interactions? I...

22 May 2014 1,770 8 View

Does anyone know what this nuclear structure is?

I created a GFP-fused mutant of my favorite transcription factor and expressed it in 293T cells. The mutation is in the putative DNA binding domain. It is not co-localizing with regions of dense...

31 March 2014 2,148 2 View