Lamya Alghanim

3 Questions 2 Answers 0 Followers

Questions related from Lamya Alghanim

Which in vitro assay can I use to know if the tested compound acts as an allosteric inhibitor of GPCR ?

I want to develop negative allosteric inhibitors of CCR2 , which is one of the GPCR , what in-vitro assay is used to know if the tested compound acting as allosteric modulator?

18 July 2023 4,134 1 View

Can I use MTT assay or Sulforhodamine B (SRB) assay to measure the cytotoxicity of CCR2 inhibitors in pancreatic cell lines ?

I have virtually searched for compounds that bind to CCR2 receptors. I have also planned to perform binding studies to determine the effect of those compounds as agonist or antagonist. Compounds...

29 May 2023 5,163 0 View

How can I interpret the following results of a homology model ?

I came across these results from a paper about homology model: verify 3D score = 104 verify 3D expected high score = 127.341 , verify 3D expected low score = 57.303. What do these results indicate?

04 May 2021 4,529 3 View