Kinga Piechura

3 Questions 6 Answers 0 Followers

Questions related from Kinga Piechura

Reduce of the oxidized form of pepide after cleavege?

Hi everybody, I want to ask if anyone of you reduced the oxidized form of peptides after cleavage peptide from the resin? I have the peptide in lyophilized form, after HPLC. I suppose that the...

07 April 2019 7,074 2 View

Coupling step during synthesis of peptides containing Histidine residue?

Hi all, What is in Your opinion the best reagent for activation of carboxyl group of Histidine (His(Trt))? In my routinely synthesis I used COMU in coupling step. But in the case of peptide...

21 April 2018 1,809 10 View

Color change during coupling in peptide synthesis?

Hi all, I've synthesised peptides using COMU as coupling reagent. Could someone explain me, why during coupling step with amino acids which contain aromatic ring (e.g.phenylalanine, Arg(Pbf)) the...

02 March 2018 3,609 5 View