Július Rajčáni

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Questions related from Július Rajčáni

What is common for latent infection with Alphaherpesviruses, especially that of HSV1/HSV2?

In the course of latency, the genomes of above mentioned viruses survive in the form of non-integrated circularized double strand (ds) DNA molecules . For diagnostic purposes the presence of this...

10 October 2017 7,297 0 View

What happens in the body upon natural infection?

When infectious virus enters the body by the so called portal of entry it may: 1. Replicate in susceptible cells 2. Behave as a foreign antigen (and/or antigen mix). Which cells are upmost...

04 April 2017 9,431 3 View

Why may viruses get attenuated when repeatedly cultured for many passages?

During a long passage history viruses may change their pathogenity and/or virulence for experimental animals and/or man. This phenomenon has a complex background. First, mutations may occur in...

01 January 2016 8,693 16 View