John Speakman

4 Questions 41 Answers 0 Followers

Questions related from John Speakman

Hi can anyone tell me what the benefits are of doing whole genome sequencing at 30x depth rather than 15x depth?

we are planning to do some whole genome sequencing of human subjects to look at signatures of selection and to check out associations of known SNPs to extended phenotypes. We have quotes for 15x...

26 September 2016 6,203 3 View

Pooling samples across individuals in RNAse and proteomics studies: what is best current practice?

Can anyone give advice on current thinking with respect to pooling samples across individuals prior to performing RNAseq or Proteomics analysis. We are planning to study transcriptomic and...

16 April 2015 9,858 18 View

Oxidative stress as a mediator of life history trade-offs: some important questions - any thoughts?

There has been much recent interest in the role played by oxidative stress as a mediator of the life history trade-off between reproduction and survival. Field studies of birds and mammals have...

03 November 2013 1,198 64 View

Differences between mouse and human adipose tissue and food intake regulation?

We recently published work on the responses of mice to differences in dietary macronutrients in Cell metabolismDietary Fat, but Not Protein or Carbohydrate, Regulates Ener... After it was...

01 January 1970 9,179 7 View