Jian Li

2 Questions 4 Answers 0 Followers

Questions related from Jian Li

Are naive T cells are the same?

Hi all, We have germline KO, CD4cre KO and Foxp3cre KO mice of the same gene. But when we sorted out naive CD4 T cells using CD4+, CD62L+ and CD25-, and subjected these cells to iTreg...

04 December 2020 7,167 3 View

Why IL-2 inhibits the induction of Treg differentiaion?

Does anyone have any idea of why IL-2 inhibits Treg differentiation? I sorted murine CD4 naive T cell and seed on anti-CD3/CD28 coated plate with TGF-beta alone or with TGF-beta and IL-2. I found...

20 March 2020 4,089 3 View