Jia-Yu Chen

4 Questions 25 Answers 0 Followers

Questions related from Jia-Yu Chen

Expression quantification/differential expression gene analysis by RNA-Seq?

RNA-Seq is very efficient to estimate gene expression level in terms of RPKM/FPKM and to perform differential expression analysis then. Which of the following methods do you prefer to calculate...

07 July 2013 9,407 15 View

How to score the similarity of DNA sequence to a motif/profile?

Any recommended method to measure the similarity?

04 April 2013 2,842 1 View

Do microRNAs in a cluster share the same ancestor?

My first quesition is, what is the definition of microRNA cluster? If Some microRNAs are next to each other in the genome, then can we call it a microRNA cluster? Are the micorRNAs in a cluster...

10 October 2012 4,481 20 View

How to calculate dN, dS?

How to calculate dN, dS? What kind of input should I prepare? And which method is better? (A) Nei-Gojobori (1986) method, (B) Yang & Nielsen (2000) method or (C) LWL85, LPB93 & LWLm methods?

09 September 2012 8,509 14 View