Jean Roudier

3 Questions 9 Answers 0 Followers

Questions related from Jean Roudier

Does anybody know of gene copy variation over the years in cells from healthy subjects?

Gene copy number variation is one type of genomic diversity among different subjects. Now, over time, people accumulate somatic mutations in their genome. Some of these may include gene...

31 August 2013 7,119 1 View

Does the HLA-DRB1 shared epitope bind citrullinated peptides?

HLA-DRB1 genes are the major genetic factor that determines susceptibility to develop rheumatoId arthritis. In 1987, Robert Winchester and Peter Gregersen demonstrated that HLA-DRB1 alleles which...

19 May 2013 5,694 13 View

Can HLA-typing help the diagnosis of psoriatic arthritis?

I am a rheumatologist seing patients with all kinds of arthritis. These days, psoriatic arthritis is extremely common. It can be typical peripheral arthritis with digitis or axial spondylitis or...

01 January 1970 6,027 7 View