What is the protocol to form a peptide bond using DIC/HOAt and DCM as a solvent? How does Fmoc-Spps work?

I want to use DIC/HOAt for forming a peptide bond with carboxylic acid group on a surface and primary amine on an oligonucleotide, using DCM as a solvent to remove the excess urea formed. 

20 June 2017 3,631 4 View