Jackie Tan

3 Questions 9 Answers 0 Followers

Questions related from Jackie Tan

Is it possible to perform QSAR studies on metals complexed with N-heterocyclic carbenes?

I am embarking on a QSAR study on organometallic compounds, i.e. metal complexed with NHC but from my preliminary readings I realized that it is not a trivial endeavour since there is a metal...

06 April 2015 3,596 7 View

How does one improve sample contrast in cryo EM?

Hi all, I am currently trying to perform cryo EM on a 360 kDa protein. However, no matter what I do, I cannot seem to obtain a discernable contrast of my samples. I have tried using a grid with...

24 October 2014 2,216 18 View

How do I proceed, after obtaining phase separation when trying to crystallize a particular protein at a condition?

I am currently trying to crystallize a protein (190kDa) and while I have identified a particular condition and concentration (19 mg/mL) through automated high throughput screening, attempts to...

11 November 2013 4,561 13 View