Can anyone suggest me the protocol to exchange PDDA (which stabilize nanoparticles) with thiol-labelled oligonucleotides?

I need to functionalize my gold nanoparticles with oligonucleotides. After synthesis they are stabilized by PDDA (Poly dimethyl diallyl ammonium chloride). I am looking for a protocol to exchange...

05 May 2016 4,794 2 View