How to improve knockout efficiency of inducible CreERT2 system, and what is the maximal dosage of tamoxifen injection?

Hi, everyone. I am working on using inducible CreERT2 system to knock out (down) target gene. I did extensive experiments to validate it. I found 2.2 mg/per adult mouse with 4 injections could...

11 November 2016 9,435 5 View