Should we use the STZ induced DM1 mouse model to study molecular mechanisms involved in secondary complications of DM1 in human diabetics?

Without insulin replacement, DM1 mice exhibit chronic, persistent hyperglycemia, glycosuria and fail to gain weight. In contrast, thanks to Banting and Best, very few human type 1 (or 2) diabetics...

03 March 2013 4,077 14 View