G. Lugo-Villarino

3 Questions 12 Answers 0 Followers

Questions related from G. Lugo-Villarino

Can Th17 cells produce TGF-beta?

I am aware that TGF-beta (in combination with IL-6) can promote Th17 (and Treg) differentiation, while inhibiting Th1 and Th2. Yet, I wonder if Th17 can produce this cytokine at steady state...

03 April 2019 4,768 3 View

Is there a good method/protocol published/available for in vitro siRNA-mediated gene silencing in freshly isolated human monocytes?

Multiple protocols are available to inactivate genes in both macrophages and dendritic cells using electroporation or lipid-based transfection of siRNA pools (not to mention viral...

13 June 2013 3,768 16 View

Does the receptor CD16 play an anti-inflammatory role by cross-talking with TLRs signals?

Blood monocyte subpopulations have been defined in humans initially, and the two major types of monocytes are the CD14++ CD16− and the CD14+ CD16+ monocytes. These cells have been shown to exhibit...

05 June 2013 598 3 View