Filip Fratev

2 Questions 21 Answers 0 Followers

Questions related from Filip Fratev

Does anyone know HCM (or mimicking HCM) mutations linked to the PDZ motif of LDB3 (ZASP)?

Does anyone know HCM (or mimicking HCM) mutations linked to the PDZ motif of LDB3 (ZASP)? If yes, what might be the functional impact of such mutation?

10 October 2013 7,798 1 View

Estrogen receptor alpha H12 transforms from "Apo" to Agonist or even Antagonist conformation only after dimmer formation?

Hi all, I performed totally of +1 us Accelerated MD (aMD) of ERa starting from the "Apo" structure (pdb id:1a52) such as many before me. However, the aMD approach speed-up the simulations around...

12 December 2012 9,470 3 View