Eóin O'Brien

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Questions related from Eóin O'Brien

Can anyone advise on the effectiveness of osmotic mini pumps (inserted subcutaneously) at increasing the serum concentration of a protein in mice?

We are currently working with NSG mice which are deficient in complement C5a. This protein is important for our disease model but due to it's short half-life repeated injections would be required...

29 September 2016 5,356 2 View

Can the THP-1 monocyte cell line be placed into the same subsets as primary monocytes i.e. classical, intermediate and non-classical monocytes?

Classical monocytes are characterised as CD14++ CD16-, Intermediate monocytes express CD14++CD16+ and Non-classical monocytes are characterised by CD14+CD16++ expression.

11 April 2014 7,513 2 View