D.P. Nagahawatta

5 Questions 6 Answers 0 Followers

Questions related from D.P. Nagahawatta

How to select substrate concentration to determine the inhibitor behavior as competitive or non-competitive?

I already calculated the IC50 value of the inhibitor against the protease enzyme. Now I need to find this inhibitor competitive non-competitive. I decided to perform the Lineweaver Burk plot, but...

22 January 2021 8,499 3 View

CDOKER energy and Binding energy; Which one is most important?

I used Discovery studio for molecular docking analysis for compound screening. Here I used binding energy, but now I am confused about which one is more important because when checking the pose of...

12 October 2020 1,040 0 View

How do I use Discovery studio result in another software?

I used the Discovery studio for molecular docking analysis and obtained the best pose by flexible docking. I need to further analyze this result using PYMOL or Ligplot, but when I saved the result...

29 September 2020 4,939 5 View

Is Sargachromenol available as a commercial compound?

I need to buy sargachromenol for HPLC standard. I tried to find it, but couldn't. If anyone knows where I can buy this, I kindly request you to inform me. Thank you.

21 September 2020 7,461 2 View

Does unfavorable bumps affect to binding energy?

I used Discovery studio for molecular docking, I used several polyphenolic compounds, and the compounds that showed the highest binding energy contain several unfavorable bumps. Is this can affect...

01 January 1970 2,319 5 View