Debasish Borbora

3 Questions 7 Answers 0 Followers

Questions related from Debasish Borbora

How to predict the effects of nsSNPs coding non-standard amino acid using different prediction softwares?

Provean, MutPred and SNP&GO fail to prediction of the effects nsSNPs coding nonstandard amino acids in the protein sequences. During homology modelling too, the non-standard amino acid were...

03 March 2017 4,656 3 View

How do you estimate haplotypes and calculate the linkage disequilibrium between two alleles?

I have the relative frequencies of the haplotypes for two loci A and B with two alleles each. Lately I have been struggling- 1. To estimate the haplotypes and 2. To calculate the LD between the...

07 July 2014 10,099 4 View

How to solve the problem of wells crumbling in 6% PAGE gels?

The wells of my gel break from one corner even before the gel polymerizes. Can anyone provide some tips and/or possible solutions to this issue? I have to separate DNA using PAGE.

01 January 2013 3,821 5 View