David Buse

4 Questions 7 Answers 0 Followers

Questions related from David Buse

Why is uncertainty in Km and Vmax estimation so high with Ki<Km in substrate inhibitions?

Dear all, I am using the following empirical equation to model substrate inhibition kinetics in a UGT-catalyzed reaction: v=vmax*S/(Km+S+S^2/Ki). In the special case when Ki is smaller than Km I...

10 October 2017 9,190 8 View

Why is uncertainty in Km and Vmax estimation so high with Ki<Km in substrate inhibitions?

Dear all, I am using the following empirical equation to model substrate inhibition kinetics in a UGT-catalyzed reaction: v=vmax*S/(Km+S+S^2/Ki). In the special case when Ki is smaller than Km I...

06 October 2017 8,229 7 View

Is there an established blood plasma ratio for insulin?

Dear community, are you aware of a blood:plasma ratio for insulin (preferably in mouse)? Can unity be assumed here?

03 March 2017 678 3 View

Is there an established blood plasma ratio for insulin?

Dear community, are you aware of a blood:plasma ratio for insulin (preferably in mouse)? Can unity be assumed here?

01 March 2017 8,222 3 View