David Zizek

3 Questions 21 Answers 0 Followers

Questions related from David Zizek

What would be the best primary outcome measure in a clinical trial of VT ablation, when the study is not powered to assess CV mortality?

In our centre, we planning to conduct a randomised VT trial in high risk ishaemic HF (EF < 40%) patients with primary prevention ICD indication. We plan to include aprox. 60 pts (30 ablation + ICD...

21 January 2018 6,569 4 View

Are beta-blockers and digoxin still warranted in heart failure patients with atrial fibrillation? What alternatives do we have?

Recent meta-analysis published in The Lancet showed that beta-blockers have no benefit in HF patients with AF. In addition, recent studies show that digoxin could be linked to increased mortality....

06 September 2014 4,935 6 View

Do you think there is still a role for cardiac resynchronizaton therapy in patients with wide QRS but non-LBBB morphology?

Most of the major studies (RAFT, MADIT CRT, CARE HF) and meta-analysis showed no benefit of CRT in patients with non-LBBB QRS morfology.

27 July 2014 8,129 17 View