David Giles

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Questions related from David Giles

What would be the most efficient way to perform CRISPR/Cas9 genome editing in murine hematopoietic stem cells prior to transplantation?

I am interested in interrogating four candidate transcription factors for their role in a mouse disease model. To do this, I would like to independently knock out these factors in bone...

19 August 2015 8,701 7 View

How do you pre-process data for multivariate analysis (NMDS, PCA), i.e. define a lower limit of detection?

I have multiplex protein levels from patient plasma and would like to compare expression patterns between groups. I plan to perform the following tests: (1) hierarchical clustering of correlation...

16 February 2015 7,445 3 View