Corey Fee

3 Questions 4 Answers 0 Followers

Questions related from Corey Fee

Looking for advice on chronic hM4Di DREADD activation?

Hi, I've generated a cell-specific DREADD model using transgenic-cre mice and AAV-DIO-hM4Di infusions. DREADD expression is excellent and behavioral changes are evident and robust after acute CNO...

05 May 2019 2,960 3 View

Do strategies exist for viral transduction of brain-wide interneurons via early postnatal injection?

Others have shown brain-wide viral transduction of neurons from intraventricular injection of AAVs in P0-1 mice (e.g. Kim et al., EJN, 2013), but even the most effective AAV8 did not penetrate...

03 March 2018 6,554 3 View

How can I create a mouse model of a Dopamine Transporter 3'-UTR variant (VNTR) that doesn't exist in mice?

I'm trying to model the human DAT1 Variable Number of Tandem Repeats (VNTR) 9- and 10-repeat alleles in mice (this is purely theoretical and for a project - will not be carried out in practice)....

01 January 2016 4,329 2 View