Clarence Hu

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Questions related from Clarence Hu

How to obtain DNA sequences of megabase-sized ecDNA in cancer cells?

i would like to analyze DNA sequences of megabase-sized ecDNA in cancer cells, especially ones in breast cancer (TNBC ideally) and lung cancer. 1. how can i obtain such DNA sequences? 2. besides...

11 September 2022 4,616 1 View

Why do reagents like doxycycline, TPA, and 5-aza induce lytic replication of Epstein-Barr virus?

Why do reagents like the ones below induce lytic replication of Epstein-Barr virus (EBV)? What's the biochemical explanation? Is this something specific to EBV? *...

01 January 1970 3,177 1 View

Ways to obtain the amino acid sequence of CRISPR Cas9 -- specifically the bridge helix, NHN, and RuvC?

Hi all, What are the best ways to obtain the amino acid sequence of CRISPR Cas9 -- specifically the bridge helix, NHN, and RuvC? Thanks.

01 January 1970 7,685 0 View