What may cause the death of mice after repeated immunization with OVA + alum?

I have tried to induce an allergic response in female Balb/c mice. Mice were immunized i.p. with OVA + alum 3 times (days 0, 10, and 20), and after the 3rd immunization, mice started to die. Does...

05 October 2018 5,216 4 View