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In 1869, the resident physician at Melbourne hospital, Australia, Thomas Ashworth for the first time observed cells from a postmortem blood sample, from a patient who had about 30 subcutaneous...
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Current methods of isolating CTCs are based on either specific cell surface markers, such as EpCAM (which limits the range of cells one can isolate), on size, density or on screening massive...
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EpCAM positive circulating tumour cells would, by definition, retain a fair amount of epithelial characteristics. Does that mean that hey are not (very) invasive and do not have (much) stem...
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