Cathy Slabber

3 Questions 1 Answers 0 Followers

Questions related from Cathy Slabber

How does Hoechst-33258 affect the electrophoretic mobility of DNA in an agarose gel?

I have run a few electrophoretic mobility assay gels recently using Hoechst-33258 and ethidium bromide in order to observe the changes in the mobility of the DNA when each are used in comparison...

01 January 2017 4,431 2 View

Can I compare the MM/GBSA values for the same ligand in 2 different proteins?

I am trying to design a molecule which is selective for one isoform of a protein over another, and I was wondering whether I could compare the MM/GBSA binding energy values for a ligand docked...

08 August 2014 2,759 4 View

Does anyone have experience with comparing different ligands - docking scores or MMGBSA?

I am working on a range of molecules for my PhD project, and I have done all the docking and MM-GBSA calculations using the Schrodinger suite of applications (Glide and Prime). But now I'm stuck -...

06 June 2014 7,916 2 View