Brandon Applewhite

2 Questions 2 Answers 0 Followers

Questions related from Brandon Applewhite

Any experience Separating/ Quantifying oligonucleotides from conjugate?

Hi, I'm attempting to determine the conjugation efficiency of a reaction between nucleic acid aptamers and PEG-maleimide. My idea was to separate free aptamer from the conjugated PEG using a...

10 October 2019 6,599 3 View

How does PEGylation affect Nucleic Acid absorbance?

Hi, I am performing a reaction in which i'm conjugating DNA oligonucleotides to an 8-arm PEG-Maleimide. I want to quantify the reaction efficiency by measuring the amount of nucleic acid remaining...

10 October 2019 4,234 1 View