The Cyp11b1 und Cyp11b2 gene are activated by the same factors. What then drives the mutually exclusive expression in the adrenal zones?

The adrenal is organized in zones (z), the z.glomerulosa synthesizes aldosterone with Cyp11b2, the z.fasciculata cortisol with Cyp11b1. The enzymes define the different zones. They are mutually...

05 November 2015 301 0 View